Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MAP kinase p38 alpha, a MAPK type protein kinase, is an environmental stress- and inflammatory cytokine-induced kinase that is associated with the regulation of gene expression, cell proliferation and cell death. p38alpha is phosphorylated by MEK3/MAP2K3 or MKK6/MAP2K6.
Western Blot Analysis Jurkat cells (lane 1) or mouse Raw cells (lane 2) were resolved by SDS-PAGE and transferred to PVDF. LS-C140539 was used at a concentration of 1 g/mL. then incubated with a goat F(ab')2 anti-rabbit IgG alkaline phosphatase conjugate secondary antibody at a 1:2000 dilution. Bands were detected with CDP-substrate using the WesternStarTM method (Tropix) and Kodak BioMax film.