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MAP4K3 / GLK

mitogen-activated protein kinase kinase kinase kinase 3

GLK, a KHS protein kinase, activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of MEKK1. The protein has a structure similar to other GCK (Group I) kinases and contains an endophilin consensus-binding sequence PPRPPPPR, which has been shown to bind the SH3 domain of endophilin I in rat. GLK is activated by UV radiation and the proinflammatory cytokine tumor necrosis factor (TNF)-alpha.

Gene Name: mitogen-activated protein kinase kinase kinase kinase 3
Family/Subfamily: Protein Kinase , KHS
Synonyms: MAP4K3, MEK kinase kinase 3, RAB8IPL1, MEKKK 3, MEKKK3, GCK-like kinase, GLK, MAPKKKK3
Target Sequences: NM_003618 NP_003609.2 Q8IVH8

☰ Filters
Antibodies (34)
Proteins (3)
Over-Expression Lysate (2)
Primary (34)
Recombinant (1)
MAP4K3 / GLK (37)
Human (34)
Mouse (14)
Rat (7)
IHC (25)
IHC-P (4)
WB (31)
Flo (14)
ELISA (23)
IF (4)
Peptide-ELISA (2)
rabbit (33)
mouse (1)
Product Group
IHCPlus (1)
IgG (29)
IgM,k (1)
monoclonal mc (1)
polyclonal pc (33)
AP Conjugated (1)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (18)
aa31-283 (7)
aa423-453 (7)
aa501-529 (7)
10-90 aa, N-terminal (1)
Gly4 (1)
aa10-59 (1)
No (37)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
MAP4K3 / GLK Antibody - Anti-MAP4K3 / GLK antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
MAP4K3 / GLK Antibody - MAP4K3 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MAP4K3 / GLK Protein - Purified recombinant protein MAP4K3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
101.1 kDa
20 µg/$1,107
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MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Mouse Polyclonal (aa501-529) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa423-453) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa423-453) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa423-453) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MAP4K3 / GLK Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using MAP4K3 Polyclonal Antibody at dilution of 1:30.
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MAP4K3 / GLK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MAP4K3 / GLK Antibody - Western blot of lysates from HepG2, MCF-7 cell line (from left to right), using MAP4K3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
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MAP4K3 / GLK Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
400 µl/$393
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa31-283) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MAP4K3 / GLK Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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MAP4K3 / GLK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MAP4K3 / GLK Antibody - Immunohistochemistry of paraffin-embedded human liver injury tissue.
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MAP4K3 / GLK Rabbit anti-Human Polyclonal (AP) Antibody
Mouse, Rat, Human
IF, IHC, WB
AP Conjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAP4K3 / GLK Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MAP4K3 / GLK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
MAP4K3 / GLK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MAP4K3 / GLK Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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MAP4K3 / GLK Rabbit anti-Human Polyclonal (aa423-453) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 37 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).