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Anti-MAP4K3 / GLK Antibody (aa423-453) LS-C99818

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MAP4K3 / GLK Antibodies

Anti-MAP4K3 / GLK Antibody (aa501-529) IHC-plus™ LS-B9106
Rabbit Polyclonal to Mouse MAP4K3 / GLK
Mouse, Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-MAP4K3 / GLK Antibody (PE) LS-C215706
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated
Anti-MAP4K3 / GLK Antibody (aa500-529, PE) LS-C215713
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MAP4K3 / GLK
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human MAP4K3 / GLK
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

MAP4K3 / GLK antibody was raised against kLH-conjugated synthetic peptide between amino acids 423-453 from C-terminal region of human GLK.
LS-E9419 - Lyophilized - 100 µg - $145.00
aa423-453

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MAP4K3 / GLK

Q8IVH8 NM_003618 NP_003609.2

MAP4K3 Antibody, MEK kinase kinase 3 Antibody, RAB8IPL1 Antibody, MEKKK 3 Antibody, MEKKK3 Antibody, GCK-like kinase Antibody, GLK Antibody, MAPKKKK3 Antibody

GLK, a KHS protein kinase, activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of MEKK1. The protein has a structure similar to other GCK (Group I) kinases and contains an endophilin consensus-binding sequence PPRPPPPR, which has been shown to bind the SH3 domain of endophilin I in rat. GLK is activated by UV radiation and the proinflammatory cytokine tumor necrosis factor (TNF)-alpha.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of anti-GLK antibody in HeLa cell lysate. Dilution for anti-GLK was 1:100; dilution for secondary goat anti-rabbit-HRP was 1:7000. A chemiluminescent kit was used for development of the Western blot. Data and protocol courtesy of Dr. Richard Lu, Partners HealthCare System at Harvard University.

Requested From: United States
Date Requested: 12/4/2016

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