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MAP4K1 / HPK1
mitogen-activated protein kinase kinase kinase kinase 1
HPK1, a KHS protein kinase, is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway. The protein has a structure similar to other GCK (Group I) kinases and contains four consensus SH3 binding motifs, which have been shown to interact with the SH3 motifs of the MAP kinase kinase kinases MLK3 and MEKK1 and several adapter proteins that couple to tyrosine kinases, including BASH, Blnk, Clnk, Crk, CrkL and Grb2. Additionally, HPK1 has been shown to be phosphorylated and activated by the tyrosine kinase c-Abl in response to genotoxic agents. At least two mRNA transcripts have been reported.
| Gene Name: | mitogen-activated protein kinase kinase kinase kinase 1 |
| Family/Subfamily: | Protein Kinase , KHS |
| Synonyms: | MAP4K1, HPK1, MEKKK 1, MEK kinase kinase 1, MHPK1 |
| Target Sequences: | NM_007181 NP_009112.1 Q92918 |
☰ Filters
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Antibodies
(36)
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MAP4K1 / HPK1
(43)
Reactivity
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(38)
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(15)
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(5)
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(6)
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(29)
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(4)
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(2)
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(20)
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(7)
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(6)
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(4)
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(4)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(43)
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(1)
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(2)
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(1)
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(1)
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(1)
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(2)
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(4)
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(1)
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(1)
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(2)
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Purified
(1)
MAP4K1 / HPK1 Goat anti-Human Polyclonal (aa2-14) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Microplate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$595
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (Leu397) Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (pSer171) (PE) Antibody
Human
DB, ELISA
PE Conjugated
200 µl/$952
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa218-267) Antibody
Human
WB
Unconjugated
100 µl/$424
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa218-267) (FITC) Antibody
Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa550-600) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa321-350) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (340-420 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa61-110) Antibody
Human
WB
Unconjugated
100 µl/$424
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal (aa61-110) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Wheat Germ Extract
GST
118.58 kDa
2 µg/$439
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
MAP4K1 / HPK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
Viewing 1-25
of 43
product results
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