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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP4K1 / HPK1 Antibody (aa348‑397) LS‑C200202
HPK1 antibody LS-C200202 is an unconjugated rabbit polyclonal antibody to HPK1 (MAP4K1) from human and mouse. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C200202-50
50 µl
Unavailable
LS-C200202-100
100 µl
Unavailable

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Product Description

HPK1 antibody LS-C200202 is an unconjugated rabbit polyclonal antibody to HPK1 (MAP4K1) from human and mouse. Validated for Peptide-ELISA and WB.
About MAP4K1 / HPK1
HPK1, a KHS protein kinase, is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway. The protein has a structure similar to other GCK (Group I) kinases and contains four consensus SH3 binding motifs, which have been shown to interact with the SH3 motifs of the MAP kinase kinase kinases MLK3 and MEKK1 and several adapter proteins that couple to tyrosine kinases, including BASH, Blnk, Clnk, Crk, CrkL and Grb2. Q92918 NM_007181 NP_009112.1

MAP4K1 Antibody, HPK1 Antibody, MEKKK 1 Antibody, MEK kinase kinase 1 Antibody, MHPK1 Antibody


Specifications

Target
Human MAP4K1 / HPK1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:10000)
Immunogen
MAP4K1 / HPK1 antibody was raised against synthetic peptide from human MEKKK 1 (aa348-397).
Epitope
aa348-397
Specificity
MEKKK 1 Antibodyantibody detects endogenous levels of MEKKK 1.
Presentation
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.
Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.

Western blot

Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.
Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.

Western blot

Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.
Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.

Western blot

Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.
Western blot of the lysates from HUVEC cells using MEKKK 1 antibody.


Requested From: 
Date Requested: 6/23/2018

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