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Anti-MAP3K8 / TPL2 Antibody (phospho-Thr290, FITC) LS-C206490

Ordering

Wt. Vol. Conc. Price
- 200 µl - Unavailable

Most Popular MAP3K8 / TPL2 Antibodies

Anti-MAP3K8 / TPL2 Antibody (C-Terminus) IHC-plus™ LS-A6858
Rabbit Polyclonal to Human MAP3K8 / TPL2
Human, Monkey, Bat, Bovine, Dog
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-MAP3K8 / TPL2 Antibody (N-Terminus) IHC-plus™ LS-A6991
Rabbit Polyclonal to Human MAP3K8 / TPL2
Human, Monkey, Bovine
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-MAP3K8 / TPL2 Antibody (aa414-445) LS-C99478
Rabbit Polyclonal to Human MAP3K8 / TPL2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human MAP3K8 / TPL2
Human
ELISA, Dot Blot (applications tested for the base form of this product only)
FITC Conjugated

Details

Human MAP3K8 / TPL2
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Fluorescein. Also available Unconjugated or conjugated with AP, Biotin, APC, PE, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750.
Immunoaffinity purified
Unmodified

Applications

  • ELISA
  • Dot Blot
  • (applications tested for the base form of this product only)

Specificity and Use

MAP3K8 / TPL2 antibody was raised against kLH-conjugated synthetic phosphopeptide around Thr290 of human COT.
pThr290
Human MAP3K8 / TPL2
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, pH 7.2, 0.09% sodium azide.
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months.
For research use only.

About MAP3K8 / TPL2

P41279 NM_005204 NP_005195.2

MAP3K8 Antibody, C-COT Antibody, Cancer Osaka thyroid oncogene Antibody, COT Antibody, Ewing sarcoma transformant Antibody, EST Antibody, MEKK8 Antibody, Proto-oncogene c-Cot Antibody, TPL2 Antibody, Tumor progression locus 2 Antibody, Protein kinase cot Antibody, Tpl-2 Antibody, ESTF Antibody

Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production.

Requested From: 
Date Requested: 3/28/2017

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