LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
MAP3K8 / TPL2 Antibody (aa414‑445, PE) LS‑C206496
Antibody
TPL2 antibody LS-C206496 is a PE-conjugated rabbit polyclonal antibody to human TPL2 (MAP3K8). Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C206496-200
200 µl
Unavailable

Popular MAP3K8 / TPL2 Products

Anti-MAP3K8 antibody LS-A6858 IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Bat, Bovine, Dog
Applications: IHC, IHC - Paraffin
Anti-MAP3K8 antibody LS-A6991 IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Bovine
Applications: IHC, IHC - Paraffin
IHC of paraffin-embedded human brain tissue, using COT (Ab-290) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded human brain, using COT (Phospho-Thr290) Antibody. The sample on the right was incubated with synthetic peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

TPL2 antibody LS-C206496 is a PE-conjugated rabbit polyclonal antibody to human TPL2 (MAP3K8). Validated for ELISA, IHC and WB.
About MAP3K8 / TPL2
Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production. P41279 NM_005204 NP_005195.2

MAP3K8 Antibody, C-COT Antibody, Cancer Osaka thyroid oncogene Antibody, COT Antibody, Ewing sarcoma transformant Antibody, EST Antibody, MEKK8 Antibody, Proto-oncogene c-Cot Antibody, TPL2 Antibody, Tumor progression locus 2 Antibody, Protein kinase cot Antibody, Tpl-2 Antibody, ESTF Antibody


Specifications

Target
Human MAP3K8 / TPL2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Phycoerythrin. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, HRP.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Epitope
aa414-445
Specificity
This COT (MAP3K8/MEKK8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-445 amino acids from the C-terminal region of human COT (MAP3K8/MEKK8).
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.09% sodium azide.
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Requested From: 
Date Requested: 6/20/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number