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Anti-MAP3K8 / TPL2 Antibody (aa396-445) LS-C31112


Wt. Vol. Conc. Price
100 µg 100 µl 1 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C426007 Biotin Conjugated
LS-C426008 HRP Conjugated
LS-C426009 FITC Conjugated

Most Popular MAP3K8 / TPL2 Antibodies

Anti-MAP3K8 / TPL2 Antibody (C-Terminus) IHC-plus™ LS-A6858
Rabbit Polyclonal to Human MAP3K8 / TPL2
Human, Monkey, Bat, Bovine, Dog
IHC - Paraffin
Immunohistochemistry Image
Anti-MAP3K8 / TPL2 Antibody (N-Terminus) IHC-plus™ LS-A6991
Rabbit Polyclonal to Human MAP3K8 / TPL2
Human, Monkey, Bovine
IHC - Paraffin
Immunohistochemistry Image
Anti-MAP3K8 / TPL2 Antibody (C-Terminus, Biotin) LS-C206498
Rabbit Polyclonal (IgG) to Human MAP3K8 / TPL2
IHC, Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human MAP3K8 / TPL2
Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit
Western blot (applications tested for the base form of this product only)


Human MAP3K8 / TPL2
Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Guinea pig, Xenopus (at least 90% immunogen sequence identity)
IgG Polyclonal
Protein A purified


  • Western blot (2.5 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

MAP3K8 / TPL2 antibody was raised against synthetic peptide located between aa396-445 of human MAP3K8 (P41279, NP_005195). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Galago, Marmoset, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Platypus (100%); Mouse, Guinea pig, Xenopus (92%); Lizard (91%); Opossum, Turkey, Chicken (84%).
Human MAP3K8


Lyophilized from PBS with 2% sucrose
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MAP3K8 / TPL2

P41279 NM_005204 NP_005195.2

MAP3K8 Antibody, C-COT Antibody, Cancer Osaka thyroid oncogene Antibody, COT Antibody, Ewing sarcoma transformant Antibody, EST Antibody, MEKK8 Antibody, Proto-oncogene c-Cot Antibody, TPL2 Antibody, Tumor progression locus 2 Antibody, Protein kinase cot Antibody, Tpl-2 Antibody, ESTF Antibody

Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production.

Western blot

Western blot
Jurkat Cell Lysate. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/25/2016

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