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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP3K7 / TAK1 Antibody (aa563‑579) IHC‑plus™ LS‑B3754
Note: This antibody replaces LS-C63200
TAK1 antibody LS-B3754 is an unconjugated rabbit polyclonal antibody to TAK1 (MAP3K7) from human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3754-50
50 µg (1 mg/ml)
Unavailable

Popular MAP3K7 / TAK1 Products

Western blot of TAK1 in cell lysates from NIH 3T3 cells using antibody at 1 ug/ml dilution.
Species: Human, Mouse
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Anti-MAP3K7 / TAK1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B18 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human MAP3K7 with DYKDDDDK tag probed with (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed (1mg/ml) in Lane B. Primary
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: ELISA, Dot Blot

Product Description

TAK1 antibody LS-B3754 is an unconjugated rabbit polyclonal antibody to TAK1 (MAP3K7) from human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About MAP3K7 / TAK1
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). O43318 NM_003188 NP_003179.1

MAP3K7 Antibody, MEKK7 Antibody, TGF-beta activated kinase 1 Antibody, TGF1a Antibody, TAK1 Antibody, TGF-beta-activated kinase 1 Antibody


Specifications

Target
Mouse MAP3K7 / TAK1
Host
Rabbit
Reactivity
Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Sheep, Xenopus (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MAP3K7 / TAK1 antibody was raised against synthetic peptide based on mouse TAK1 (residues 563-579) (1) with a cysteine C residue added and the peptide coupled to KLH.
Epitope
aa563-579
Specificity
Detects an ~70 kD protein, corresponding to the apparent molecular mass of TAK1 on SDS-PAGE immunoblots.
Usage
Immunohistochemistry: LS-B3754 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3754 was determined to be 10 ug/ml.
Presentation
PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.

Immunohistochemistry

Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.
Anti-MAP3K7 / TAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3754 concentration 5 ug/ml.


Requested From: 
Date Requested: 6/23/2018

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