Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Mouse Monoclonal [clone 5C4] (IgG2b,k) to Human MAP3K5 / ASK1
Human
Western blot, ELISA
Unconjugated
Rabbit Polyclonal (IgG) to Human MAP3K5 / ASK1
Human, Mouse
IHC
Unconjugated
Details
Human MAP3K5 / ASK1
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified
Applications
IHC (1:50 - 1:100)
Specificity and Use
MAP3K5 / ASK1 antibody was raised against synthetic non-phosphopeptide corresponding to human ASK1 around the phosphorylation site of serine 966 (S-I-SP-L-P).
Recognizes human ASK1. Species cross-reactivity: mouse.
Suitable for use in Immunohistochemistry:1:50-1:100.
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation.