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MAP3K11 / MLK3

mitogen-activated protein kinase kinase kinase 11

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Gene Name: mitogen-activated protein kinase kinase kinase 11
Family/Subfamily: Protein Kinase , MLK(MAP3K)
Synonyms: MAP3K11, Mixed lineage kinase 3, MLK3, Protein-tyrosine kinase PTK1, PTK1, SPRK, MLK-3, MEKK11
Target Sequences: NM_002419 NP_002410.1 Q16584

☰ Filters
Antibodies (29)
Proteins (4)
Over-Expression Lysate (2)
Primary (29)
Recombinant (2)
MAP3K11 / MLK3 (33)
Human (29)
Mouse (19)
Rat (12)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (3)
Monkey (4)
Rabbit (3)
IHC (8)
IHC-Fr (1)
IHC-P (3)
WB (22)
ELISA (14)
IF (2)
Peptide-ELISA (2)
rabbit (27)
mouse (2)
Product Group
IHCPlus (2)
IgG (19)
IgG2a,k (1)
IgM,k (1)
monoclonal mc (2)
polyclonal pc (27)
3D11 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (18)
aa719-768 (4)
610-690 aa (2)
pThr277/Ser281 (2)
Ab-674 (1)
C-Terminus (1)
aa640-689 (1)
No (32)
Yes (1)
GST, N-terminus (2)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
MAP3K11 / MLK3 Antibody - IHC with MAP3K11 antibody on frozen human spleen.
Select
MAP3K11 / MLK3 Mouse anti-Human Monoclonal (3D11) Antibody
Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
50 µg/$460
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (pThr277/Ser281) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$328; 100 µl/$419
MAP3K11 / MLK3 Antibody - Western blot analysis of MLK3 (pT277/S281) expression in HEK293T (A); NIH3T3 (B); PC12 (C) whole cell lysates.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (pThr277/Ser281) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$315
MAP3K11 / MLK3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MAP3K11 / MLK3 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
WB
Unconjugated
100 µl/$688
MAP3K11 / MLK3 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using MAP3K11 Polyclonal Antibody at dilution of 1:40.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (610-690 aa) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MAP3K11 / MLK3 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MLK3 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (aa640-689) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
MAP3K11 / MLK3 Antibody - Immunohistochemistry image of paraffin-embedded human skeletal muscle tissue at a dilution of 1:100
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
MAP3K11 / MLK3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MLK3 antibody.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (Ab-674) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100 µg/$357
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
MAP3K11 / MLK3 Antibody
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
MAP3K11 / MLK3 Antibody - Western blot of Phospho-MLK3 (S674) antibody
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (610-690 aa) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MAP3K11 / MLK3 Antibody - Western blot analysis of MLK3 in lysates of NIH 3T3 cells using MLK3 antibody.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$425
MAP3K11 / MLK3 Antibody - MAP3K11 / MLK3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (aa719-768) Antibody
Human
WB
Unconjugated
100 µl/$424
MAP3K11 / MLK3 Antibody - MAP3K11 / MLK3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (aa719-768) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MAP3K11 / MLK3 Antibody - MAP3K11 / MLK3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal (aa719-768) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MAP3K11 / MLK3 Antibody - Western blot of MAP3K11 Antibody in mouse lung tissue lysates (35 ug/lane). MAP3K11 (arrow) was detected using the purified antibody.
Select
MAP3K11 / MLK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 33 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).