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Anti-MAP3K11 / MLK3 Antibody (C-Terminus) LS-C16573

Catalog Size Price
LS-C16573-100 100 µl (0.25 mg/ml) Unavailable

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Rabbit Polyclonal (IgG) to Human MAP3K11 / MLK3
Human, Monkey, Mouse, Rat, Hamster
Western blot


Human MAP3K11 / MLK3
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


Western blot (1:1000)

Specificity and Use

MAP3K11 / MLK3 antibody was raised against synthetic peptide corresponding to residues near the carboxy terminus of human MLK3 (KLH coupled).
Detects endogenous levels of total MLK3 (Mr 92kD). Does not cross-react with MLK1, MLK2 and other mixed lineage kinases. Species cross-reactivity: Mouse, rat, hamster and monkey.
Suitable for use in Western Blot. Western Blot: 1:1000.


10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MAP3K11 / MLK3

Q16584 NM_002419 NP_002410.1

MAP3K11 Antibody, Mixed lineage kinase 3 Antibody, MLK3 Antibody, Protein-tyrosine kinase PTK1 Antibody, PTK1 Antibody, SPRK Antibody, MLK-3 Antibody, MEKK11 Antibody

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Requested From: 
Date Requested: 5/24/2018

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