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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP3K11 / MLK3 Antibody (C‑Terminus) LS‑C16573
MLK3 antibody LS-C16573 is an unconjugated rabbit polyclonal antibody to MLK3 (MAP3K11) from human, mouse, rat and other species. Validated for WB.
Antibody
Catalog
Size
Price
LS-C16573-100
100 µl (0.25 mg/ml)
$530

Popular MAP3K11 / MLK3 Products

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Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

MLK3 antibody LS-C16573 is an unconjugated rabbit polyclonal antibody to MLK3 (MAP3K11) from human, mouse, rat and other species. Validated for WB.

Specifications

Target
Human MAP3K11 / MLK3
Synonyms
MAP3K11, Mixed lineage kinase 3, MLK3, Protein-tyrosine kinase PTK1, PTK1, SPRK, MLK-3, MEKK11
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
MAP3K11 / MLK3 antibody was raised against synthetic peptide corresponding to residues near the carboxy terminus of human MLK3 (KLH coupled).
Epitope
C-Terminus
Specificity
Detects endogenous levels of total MLK3 (Mr 92kD). Does not cross-react with MLK1, MLK2 and other mixed lineage kinases. Species cross-reactivity: Mouse, rat, hamster and monkey.
Usage
Suitable for use in Western Blot. Western Blot: 1:1000.
Presentation
10 mM HEPES-Sodium, pH 7.5, 150 mM NaCl, 100 ug/ml BSA, 50% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About MAP3K11 / MLK3
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. Q16584 NM_002419 NP_002410.1


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Requested From: United States
Date Requested: 11/13/2018

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