MAP2K7 / MEK7

mitogen-activated protein kinase kinase 7

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

☰ Filters

Products

Antibodies (77)

ELISA Kits (8)

Proteins (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (4)

Over-Expression Lysate (2)

Primary (77)

Recombinant (5)

Sandwich (1)

Target

MAP2K7 / MEK7 (92)

Reactivity

Human (73)

Mouse (53)

Rat (29)

Bat (5)

Bovine (6)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (7)

Horse (6)

Monkey (4)

Pig (8)

Rabbit (7)

Sheep (5)

Xenopus (3)

more less

Application

IHC (19)

IHC-P (6)

WB (73)

Flo (2)

ELISA (22)

ICC (2)

IF (14)

IP (3)

Peptide-ELISA (6)

Host

rabbit (68)

mouse (9)

Product Group

IHCPlus (2)

Isotype

IgG (32)

IgG1 (8)

IgG1,k (1)

Clonality

monoclonal mc (9)

polyclonal pc (68)

Clone

2G5 (1)

400000 (1)

4E5 (1)

Format

96-Well Microplate (4)

96-Well Strip Plate (4)

APC (2)

APC Conjugated (5)

Azide-free (1)

Biotin Conjugated (8)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (5)

Preservative Free (1)

Unconjugated (39)

more less

Epitope

aa113-388 (8)

aa181-429 (8)

aa206-233 (7)

C-Terminus (4)

aa287-336 (4)

210-290 aa (3)

pSer271 (3)

pThr275 (3)

Ile264 (1)

aa1-50 (1)

aa2-40 (1)

aa236-285 (1)

aa24-40 (1)

aa241-290 (1)

aa325-360 (1)

aa363-396 (1)

aa4-29 (1)

pSer271/Thr275 (1)

more less

Publications

No (92)

Sample Type

Adherent Cell Cultures (3)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

Mouse/Human/Rat Phospho-MAP2K7 / MEK7 (Thr275) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1688

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$772

Select

Mouse/Human/Rat MAP2K7 / MEK7 (Cell-Based ELISA) ELISA Kit - LS-F2125

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

Select

MAP2K7 / MEK7 Antibody (phospho-Ser271) LS-C199215

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (pSer271) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

IHC-plus™ MAP2K7 / MEK7 Antibody (aa206-233) LS-B15661

(4.0) Rating

Antibody:

MAP2K7 / MEK7 Rabbit anti-Mouse Polyclonal (aa206-233) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

IHC-plus™ MAP2K7 / MEK7 Antibody LS-B16550

(4.0) Rating

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$485

Select

MAP2K7 / MEK7 Antibody (clone 400000) LS-C758982

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (400000) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

Select

MAP2K7 / MEK7 Antibody (aa1-50) LS-C290878

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

MAP2K7 / MEK7 Antibody (clone 4E5) LS-C169440

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (4E5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

MAP2K7 / MEK7 Antibody LS-C331968

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539

Select

MAP2K7 / MEK7 Antibody (phospho-Ser271/Thr275) LS-C182038

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (pSer271/Thr275) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 Blots/$863

Select

MAP2K7 / MEK7 Antibody (aa287-336) LS-C111215

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (aa287-336) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

Human MAP2K7 / MEK7 Protein (Recombinant His-T7) (aa113-388) - LS-G15339

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.2 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

Select

MAP2K7 / MEK7 Antibody (aa2-40) LS-C407976

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (aa2-40) Antibody

Reactivity:

Mouse, Dog, Sheep, Rat, Pig, Bat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

MAP2K7 / MEK7 Antibody LS-C16401

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$786

Select

MAP2K7 / MEK7 Antibody (HRP) LS-C547801

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

HRP Conjugated

Price:

100 µl/$1,017

Select

MAP2K7 / MEK7 Antibody (Biotin) LS-C527704

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,017

Select

MAP2K7 / MEK7 Antibody (FITC) LS-C537666

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

FITC Conjugated

Price:

100 µl/$1,017

Select

MAP2K7 / MEK7 Antibody (PE) LS-C655836

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

PE Conjugated

Price:

100 µl/$1,017

Select

MAP2K7 / MEK7 Antibody (APC) LS-C517980

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

APC Conjugated

Price:

100 µl/$1,017

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

MAP2K7 / MEK7 Antibody (aa206-233) LS-C329794

Antibody:

MAP2K7 / MEK7 Rabbit anti-Mouse Polyclonal (aa206-233) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MAP2K7 / MEK7 Antibody LS-C490437

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

MAP2K7 / MEK7 Antibody (clone 2G5) LS-C133407

Antibody:

MAP2K7 / MEK7 Mouse anti-Human Monoclonal (2G5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

MAP2K7 / MEK7 Antibody (aa4-29) LS-C83975

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (aa4-29) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$556

Select

MAP2K7 / MEK7 Antibody (210-290 aa) LS-C381018

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (210-290 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MAP2K7 / MEK7 Antibody (210-290 aa) LS-C381380

Antibody:

MAP2K7 / MEK7 Rabbit anti-Human Polyclonal (210-290 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Viewing 1-25 of 92 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.