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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP2K1 / MKK1 / MEK1 Antibody (phospho‑Ser298) LS‑C175872
MEK1 antibody LS-C175872 is an unconjugated rabbit polyclonal antibody to human MEK1 (MAP2K1 / MKK1). Validated for WB.
Catalog
Size
Price
LS-C175872-100
100 µl
Unavailable

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Applications: IHC, IHC - Paraffin, Western blot

Product Description

MEK1 antibody LS-C175872 is an unconjugated rabbit polyclonal antibody to human MEK1 (MAP2K1 / MKK1). Validated for WB.
About MAP2K1 / MKK1 / MEK1
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Q02750 NM_002755 NP_002746.1

MAP2K1 Antibody, ERK activator kinase 1 Antibody, MAPK/ERK kinase 1 Antibody, MAPKK 1 Antibody, MKK1 Antibody, PRKMK1 Antibody, MEK 1 Antibody, MAP kinase kinase 1 Antibody, MAPKK1 Antibody, MEK1 Antibody


Specifications

Target
Human MAP2K1 / MKK1 / MEK1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
Synthetic phosphopeptide around pSer298 of human MEK1
Epitope
pSer298
Specificity
Human MEK1
Presentation
PBS, pH 7.2, 15 mM sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.
Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.

Western blot

Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.
Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.

Western blot

Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.
Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.

Western blot

Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.
Western blot of p-MEK1 (S298) pAb in extracts from HeLa and HepG2 cells.


Requested From: 
Date Requested: 6/19/2018

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