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Anti-MAP1LC3A / LC3A Antibody (aa2-15) LS-C188005

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $595
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MAP1LC3A / LC3A Antibodies

Anti-MAP1LC3A / LC3A Antibody (aa97-106) IHC-plus™ LS-B5129
Goat Polyclonal to Human MAP1LC3A / LC3A
Human, Monkey, Mouse, Rat, Bovine, Hamster, Pig, Xenopus
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-MAP1LC3A / LC3A Antibody LS-C165694
Mouse Monoclonal (IgG1,k) to Human MAP1LC3A / LC3A
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human MAP1LC3A / LC3A
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Pig, Fish, Zebrafish
Immunofluorescence, Western blot
Unconjugated

Details

Human MAP1LC3A / LC3A
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Pig, Fish, Zebrafish (tested or 100% immunogen sequence identity)
Dog (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • Immunofluorescence
  • Western blot (1:100 - 1:250)

Specificity and Use

MAP1LC3A / LC3A antibody was raised against synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminal region of LC3A (NP_115903.1; NP_852610.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Pig, Opossum, Guinea pig, Salmon, Zebrafish (100%); Ferret, Dog, Cat, Lizard, Catfish, Stickleback, Medaka, Pufferfish (93%); Chicken, Pike (86%).
aa2-15
Recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane. Recognizes both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B.

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About MAP1LC3A / LC3A

Q9H492 NM_032514 NP_115903.1

MAP1LC3A Antibody, ATG8E Antibody, LC3 Antibody, LC3A Antibody, MAP1BLC3 Antibody, MAP1A/1B light chain 3 A Antibody, MAP1A/MAP1B LC3 A Antibody, MAP1A/MAP1B light chain 3 A Antibody, MAP1ALC3 Antibody

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.

Western blot

Western blot
Western blot of LC3 expression on Atg5 knockout and wild type cells using Rabbit anti-Human MAP1LC3A/B . Image courtesy of Dr. R. Kapito, Stanford University

Western blot

Western blot
HeLa lysate probed with Rabbit anti-Human MAP1LC3A/B (N-terminal) followed by Sheep anti-Rabbit IgG:HRP

Requested From: United States
Date Requested: 12/4/2016

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