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Anti-Mannose Receptor / CD206 Antibody (clone 7-450) LS-C58102

Note: This antibody replaces LS-C58101

Ordering

Wt. Vol. Conc. Price
100 µg - - $270
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular Mannose Receptor / CD206 Antibodies

Anti-Mannose Receptor / CD206 Antibody (clone 5C11) IHC-plus™ LS-B5474
Mouse Monoclonal [clone 5C11] (IgG1,k) to Human Mannose Receptor / CD206
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-Mannose Receptor / CD206 Antibody (aa359-388) IHC-plus™ LS-B9805
Rabbit Polyclonal to Human Mannose Receptor / CD206
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 7-450] (IgG2a) to Human Mannose Receptor / CD206
Human
IHC - Frozen
Unconjugated

Details

Human Mannose Receptor / CD206
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [7-450]
Unconjugated
Affinity purified
Unmodified

Applications

IHC - Frozen (1:50 - 1:500)

Specificity and Use

Mannose Receptor / CD206 antibody was raised against monocyte-derived dendritic cells.
Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About Mannose Receptor / CD206

P22897 NM_002438 NP_002429.1

MRC1 Antibody, BA541I19.1 Antibody, CLEC13D Antibody, CD206 Antibody, CD206 antigen Antibody, Macrophage mannose receptor 1 Antibody, Mannose Receptor Antibody, Macrophage mannose receptor Antibody, MMR Antibody, Mannose receptor, C type 1 Antibody, MRC1L1 Antibody, CLEC13DL Antibody

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages.

Immunohistochemistry

Immunohistochemistry
Staining of frozen Human Tonsil stained with Mouse anti Human CD206.
 

Requested From: United States
Date Requested: 12/8/2016

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