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MAN1B1

Mannosidase, Alpha, Class 1B, Member 1

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

Gene Name: Mannosidase, Alpha, Class 1B, Member 1
Synonyms: MAN1B1
Target Sequences: NM_016219 NP_057303.2 Q9UKM7

☰ Filters
Antibodies (6)
Proteins (5)
Over-Expression Lysate (2)
Primary (6)
Recombinant (3)
MAN1B1 (11)
Human (6)
Mouse (2)
Rat (2)
IHC (1)
IHC-P (1)
WB (6)
ELISA (2)
IF (1)
Peptide-ELISA (1)
rabbit (5)
mouse (1)
IgG (4)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (5)
6B1 (1)
Unconjugated (6)
100-180 aa, Internal (1)
aa414-699 (1)
No (11)
6His, C-terminus (2)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Low endotoxin level (2)
MAN1B1 Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
MAN1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MAN1B1 Antibody - MAN1B1 monoclonal antibody (M01), clone 6B1. Western blot of MAN1B1 expression in HepG2.
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MAN1B1 Mouse anti-Human Monoclonal (6B1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
MAN1B1 Antibody - IHC of paraffin-embedded SCC25 xenograft using MAN1B1 antibody at 1:100 dilution.
Select
MAN1B1 Rabbit anti-Human Polyclonal (aa414-699) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$408
MAN1B1 Antibody - Western blot of MAN1B1 antibody
Select
MAN1B1 Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MAN1B1 Antibody - Western blot of 3T3 cell lysate using MAN1B1 Antibody
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MAN1B1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
MAN1B1 Antibody - Western blot analysis of extracts of various cell lines, using MAN1B1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
MAN1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAN1B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
79.4 kDa
100 µg/$494
MAN1B1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MAN1B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
79.4 kDa
20 µg/$150
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
68.7kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
68.7 kDa
10 µg/$376; 50 µg/$526
Viewing 1-11 of 11 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).