MAML2

mastermind-like 2 (Drosophila)

MAML2 is a member of the Mastermind-like family of proteins. All family members are proline and glutamine-rich, and contain a conserved basic domain that binds the ankyrin repeat domain of the intracellular domain of the Notch receptors (ICN1-4) in their N-terminus, and a transcriptional activation domain in their C-terminus. This protein binds to an extended groove that is formed by the interaction of CBF1, Suppressor of Hairless, LAG-1 (CSL) with ICN, and positively regulates Notch signaling. High levels of expression of this gene have been observed in several B cell-derived lymphomas. Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas, while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL). Copy number variation in the polyglutamine tract has been observed.

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Products

Antibodies (29)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (29)

Recombinant (1)

Target

MAML2 (32)

Reactivity

Human (24)

Mouse (9)

Application

IHC (5)

IHC-P (6)

WB (21)

Flo (4)

ELISA (11)

IF (5)

IP (2)

Peptide-ELISA (1)

Host

rabbit (18)

mouse (11)

Isotype

IgG (10)

IgG2a (3)

IgG2a,k (6)

Clonality

monoclonal mc (11)

polyclonal pc (18)

Clone

MAML2/1302 (3)

MMLP2-1 (2)

Format

APC Conjugated (1)

Azide-free (2)

Biotin Conjugated (4)

BSA-free (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Ready-to-Use (1)

Unconjugated (15)

Epitope

aa169-218 (4)

aa324-373 (4)

aa1100-C-term (2)

aa250-300 (1)

aa780-814 (1)

aa796-895 (1)

Publications

No (32)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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MAML2 Antibody (clone MMLP2-1) LS-C489993

Antibody:

MAML2 Mouse anti-Human Monoclonal (MMLP2-1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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MAML2 Antibody (clone MMLP2-1, Azide-free, BSA-free) LS-C490030

Antibody:

MAML2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MMLP2-1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Azide-free, BSA-free

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MAML2 Antibody (clone MAML2/1302) LS-C761735

Antibody:

MAML2 Mouse anti-Human Monoclonal (MAML2/1302) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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MAML2 Antibody (clone MAML2/1302, Azide-free, BSA-free) LS-C761736

Antibody:

MAML2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MAML2/1302) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

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MAML2 Antibody (clone MAML2/1302, Ready-to-Use) LS-C761737

Antibody:

MAML2 Mouse anti-Human Monoclonal (Ready-to-Use) (MAML2/1302) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

Select

MAML2 Antibody LS-C680814

Antibody:

MAML2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MAML2 Antibody (aa1100-C-term) LS-C286672

Antibody:

MAML2 Rabbit anti-Human Polyclonal (aa1100-C-term) Antibody

Reactivity:

Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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MAML2 Antibody (aa1100-C-term) LS-C287552

Antibody:

MAML2 Rabbit anti-Human Polyclonal (aa1100-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

MAML2 Antibody (aa796-895) LS-C308866

Antibody:

MAML2 Mouse anti-Human Monoclonal (aa796-895) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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MAML2 Antibody (HRP) LS-C543043

Antibody:

MAML2 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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MAML2 Antibody (Biotin) LS-C522911

Antibody:

MAML2 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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MAML2 Antibody (FITC) LS-C532955

Antibody:

MAML2 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

MAML2 Antibody (PE) LS-C651155

Antibody:

MAML2 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

MAML2 Antibody (APC) LS-C514696

Antibody:

MAML2 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

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MAML2 Antibody LS-C780095

Antibody:

MAML2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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MAML2 Antibody LS-C803865

Antibody:

MAML2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MAML2 Antibody (aa169-218) LS-C116146

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa169-218) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MAML2 Antibody (aa169-218, HRP) LS-C435872

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa169-218) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MAML2 Antibody (aa169-218, FITC) LS-C435870

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa169-218) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

MAML2 Antibody (aa324-373) LS-C170175

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa324-373) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MAML2 Antibody (aa324-373, HRP) LS-C435869

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa324-373) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MAML2 Antibody (aa324-373, Biotin) LS-C435867

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa324-373) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MAML2 Antibody (aa324-373, FITC) LS-C435868

Antibody:

MAML2 Rabbit anti-Mouse Polyclonal (aa324-373) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MAML2 Antibody (aa780-814) LS-C356751

Antibody:

MAML2 Rabbit anti-Human Polyclonal (aa780-814) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MAML2 Antibody (aa250-300) LS-C287551

Antibody:

MAML2 Rabbit anti-Human Polyclonal (aa250-300) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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