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MAGED1 / NRAGE

melanoma antigen family D, 1

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Gene Name: melanoma antigen family D, 1
Synonyms: MAGED1, DLXIN-1, MAGE-D1 antigen, Melanoma antigen family D, 1, NRAGE, MAGE tumor antigen CCF, Melanoma-associated antigen D1
Target Sequences: NM_006986 NP_008917.3

Publications (1)

1
NRAGE promotes the malignant phenotype of hepatocellular carcinoma. Shimizu D, Kanda M, Sugimoto H, Sueoka S, Takami H, Ezaka K, Tanaka Y, Hashimoto R, Okamura Y, Iwata N, Tanaka C, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y. Oncology letters. 2016 11:1847-1854. (WB; Human) [Full Text Article] [PubMed:26998088] [PMC:PMC4774420] Related Antibodies: LS-C100414.

☰ Filters
Antibodies (32)
Proteins (10)
Over-Expression Lysate (6)
Primary (32)
Recombinant (4)
MAGED1 / NRAGE (42)
Human (32)
Mouse (19)
Rat (12)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (8)
IHC (18)
IHC-P (3)
WB (31)
ELISA (14)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (29)
mouse (2)
goat (1)
IgG (23)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (30)
1305CT862.157.127 (1)
1E1 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (19)
aa426-456 (7)
aa516-565 (4)
aa20-224 (1)
aa53-295 (1)
aa73-254 (1)
No (41)
Yes (1)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (6)
Human (7)
293T Cells (3)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (3)
Purified (3)
MAGED1 / NRAGE Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
MAGED1 / NRAGE Rabbit anti-Rat Polyclonal (aa53-295) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
200 µl/$957
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
MAGED1 / NRAGE Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using MAGED1 antibodyat dilution of 1:100 (40x lens).
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAGED1 / NRAGE Antibody - Immunohistochemistry of paraffin-embedded human glioma cancer at dilution 1:100
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MAGED1 / NRAGE Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using MAGED1 Polyclonal Antibody at dilution of 1:30.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MAGED1 / NRAGE Antibody - Immunohistochemistry of paraffin-embedded Human tonsil using MAGED1 Polyclonal Antibody at dilution of 1:30.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa426-456) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MAGED1 / NRAGE Antibody - Immunohistochemistry of paraffin-embedded human glioma cancer at dilution 1:100
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
MAGED1 / NRAGE Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MAGED1 / NRAGE Antibody - Western blot of MAGED1 pAb in extracts from A549 cells.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
MAGED1 / NRAGE Antibody - MAGED1 monoclonal antibody (M06), clone 1E1. Western blot of MAGED1 expression in Jurkat.
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MAGED1 / NRAGE Mouse anti-Human Monoclonal (1E1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
MAGED1 / NRAGE Antibody - Western blot of lysates from Jurkat, 293 cell line (from left to right) with MAGED1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
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MAGED1 / NRAGE Mouse anti-Human Monoclonal (aa20-224) (1305CT862.157.127) Antibody
Human
WB
Unconjugated
400 µl/$393
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Select
MAGED1 / NRAGE Rabbit anti-Human Polyclonal (PE) Antibody
Rabbit, Mouse, Human
WB
PE Conjugated
100 µl/$937
MAGED1 / NRAGE Antibody - MAGED1 / NRAGE antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MAGED1 / NRAGE Rabbit anti-Human Polyclonal (aa516-565) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
Select
MAGED1 / NRAGE Goat anti-Human Polyclonal (aa73-254) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$941
Viewing 1-25 of 42 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).