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Anti-MAGEA3 Antibody (clone 2E11) LS-C175505

Catalog Size Price
LS-C175505-100 100 µl (1 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 2E11] (IgG2b) to Human MAGEA3
Human
Western blot
Unconjugated

Details

Human MAGEA3
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [2E11]
Unconjugated
Protein A/G purified
Unmodified

Applications

Western blot (1:2000)

Specificity and Use

MAGEA3 antibody was raised against full length human recombinant protein of human MAGEA3 (NP_005353) produced in HEK293T cell.
Human MAGEA3

Packaging

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MAGEA3

P43357 U03735 AAA17446.1

MAGEA3 Antibody, Antigen MZ2-D Antibody, Cancer/testis antigen 1.3 Antibody, CT1.3 Antibody, HYPD Antibody, MAGE-3 antigen Antibody, Melanoma-associated antigen 3 Antibody, HIP8 Antibody, MAGE3 Antibody, Melanoma antigen family A, 3 Antibody

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAGEA3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAGEA3.

Requested From: 
Date Requested: 10/20/2017

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