MAGEA2

melanoma antigen family A, 2

Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Negatively regulates acetylation and sumoylation of PML and represses PML-induced p53/TP53 acetylation and activation.

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Products

Antibodies (15)

Proteins (7)

Type

Over-Expression Lysate (6)

Primary (15)

Recombinant (1)

Target

MAGEA2 (22)

Reactivity

Human (15)

Application

IHC (7)

IHC-P (1)

WB (15)

ELISA (9)

Peptide-ELISA (1)

Host

rabbit (14)

mouse (1)

Isotype

IgG (7)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (14)

Clone

1H4 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa81-108 (7)

aa23-72 (4)

Publications

No (22)

Tag

GST (1)

Myc-DDK (Flag) (6)

Species

Human (4)

Source

293T Cells (3)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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MAGEA2 Antibody (aa81-108) LS-C99933

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MAGEA2 Antibody (aa81-108) LS-C327795

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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MAGEA2 Antibody (aa81-108, Biotin) LS-C279070

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MAGEA2 Antibody (aa81-108, FITC) LS-C279071

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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MAGEA2 Antibody (aa81-108, APC) LS-C279069

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MAGEA2 Antibody (aa81-108, Azide-free, HRP) LS-C279072

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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MAGEA2 Antibody (aa81-108, PE) LS-C279073

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa81-108) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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MAGEA2 Antibody (clone 1H4) LS-C197640

Antibody:

MAGEA2 Mouse anti-Human Monoclonal (1H4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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MAGEA2 Antibody LS-C779791

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MAGEA2 Antibody LS-C780873

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MAGEA2 Antibody LS-C802294

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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MAGEA2 Antibody (aa23-72) LS-C135649

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa23-72) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MAGEA2 Antibody (aa23-72, HRP) LS-C466866

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa23-72) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MAGEA2 Antibody (aa23-72, Biotin) LS-C466864

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa23-72) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MAGEA2 Antibody (aa23-72, FITC) LS-C466865

Antibody:

MAGEA2 Rabbit anti-Human Polyclonal (aa23-72) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77281

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

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Human MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77282

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

Select

Human MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77283

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

Select

Human MAGEA2 Protein (Recombinant GST) (Full Length) - LS-G29249

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

60.28 kDa

Price:

10 µg/$479; 25 µg/$670

Select

MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104994

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

Select

MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104996

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

Select

MAGEA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116020

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

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