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MAGEA1 / MAGE 1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGE was originally isolated from human melanoma cells as an antigen that is recognizes by cytolytic T lymphocytes. It has since been documented in other carcinomas. In addition, expression has been documented in highly proliferating germ cells.
| Gene Name: | melanoma antigen family A, 1 (directs expression of antigen MZ2-E) |
| Synonyms: | MAGEA1, Antigen MZ2-E, Cancer/testis antigen 1.1, CT1.1, MAGE-1 antigen, MAGE1A, Melanoma antigen family A 1, Melanoma antigen MAGE-1, MAGE 1, MAGE1, Melanoma-associated antigen 1 |
| Target Sequences: | NM_004988 NP_004979.3 P43355 |
Publications (2)
1
Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Planells-Palop V, Hazazi A, Feichtinger J, Jezkova J, Thallinger G, Alsiwiehri NO, Almutairi M, Parry L, Wakeman JA, McFarlane RJ. Molecular cancer. 2017 16:84. (ICC, IHC-P; Human)
[Full Text Article]
[PubMed:28446200]
[PMC:PMC5406905]
2
Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma. Kenji Murata , Munehide Nakatsugawa , Muhammed A Rahman, Linh T Nguyen, Douglas G Millar, David T Mulder, Kenji Sugata, Hiroshi Saijo, Yukiko Matsunaga, Yuki Kagoya, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Brian D Burt, Dalam Ly, Kayoko Saso, Alexandra Easson, David P Goldstein, Michael Reedijk, Danny Ghazarian, Trevor J Pugh, Marcus O Butler, Tak W Mak, Pamela S Ohashi, Naoto Hirano. eLife. 2020 Apr;9:e53244. [Full Text Article]
[PubMed:32314731]
[PMC:PMC7234812]
Related Antibodies: LS-C391567.
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MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal (aa260-309) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (MAAZ2) Antibody
Human
IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Yeast
6His, N-terminus
36.31 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (MA454) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MA454) Antibody
Rat, Human
Flo, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Ready-to-Use) (MA454) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal (aa143-173) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$786
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IF, IHC, IP, WB
HRP Conjugated
100 µl/$1,017
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, IHC, IP, WB
Biotin Conjugated
100 µl/$1,017
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, IHC, IP, WB
FITC Conjugated
100 µl/$1,017
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, IHC, IP, WB
PE Conjugated
100 µl/$1,017
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, IHC, IP, WB
APC Conjugated
100 µl/$1,017
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (MZ2E/838) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Ready-to-Use) (MZ2E/838) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MZ2E/838) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (SPM282) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM282) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Cancer
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
MAGEA1 / MAGE 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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