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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAdCAM‑1 Antibody (clone MECA‑367, Biotin) LS‑C106210
Antibody
MAdCAM-1 antibody LS-C106210 is a biotin-conjugated rat monoclonal antibody to mouse MAdCAM-1. Validated for Flow.
Catalog
Size
Price
LS-C106210-50
50 µg
Unavailable
LS-C106210-100
100 µg
Unavailable
LS-C106210-500
500 µg
Unavailable

Popular MAdCAM-1 Products

Antibody
Species: Human
Applications: Western blot, ELISA, Functional Assay
Antibody
Species: Human
Applications: Western blot, Flow Cytometry, ELISA
Anti-MADCAM1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3316 concentration 10 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Antibody
Species: Mouse
Applications: IHC, Immunoprecipitation, Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Flow Cytometry

Product Description

MAdCAM-1 antibody LS-C106210 is a biotin-conjugated rat monoclonal antibody to mouse MAdCAM-1. Validated for Flow.
About MAdCAM-1
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. Q13477 NM_130762 AAC51354.1

MADCAM1 Antibody, HMAdCAM-1 Antibody, MACAM1 Antibody, MAdCAM-1 Antibody


Specifications

Target
Mouse MAdCAM-1
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [MECA-367]
Conjugations
Biotin
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
MAdCAM-1 antibody was raised against mouse MADCAM1
Usage
The MECA-367 antibody has been tested by flow cytometric analysis of mouse bone marrow cells and splenocyte suspensions and can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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