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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAD1L1 / MAD1 Antibody (clone 9B10) LS‑C82255
MAD1 antibody LS-C82255 is an unconjugated mouse monoclonal antibody to human MAD1 (MAD1L1). Validated for IF, IP and WB.
Catalog
Size
Price
LS-C82255-50
50 µl
Unavailable

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Product Description

MAD1 antibody LS-C82255 is an unconjugated mouse monoclonal antibody to human MAD1 (MAD1L1). Validated for IF, IP and WB.
About MAD1L1 / MAD1
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding. Q9Y6D9 NM_003550 NP_003541.2

MAD1L1 Antibody, HMAD1 Antibody, MAD1 Antibody, MAD1-like protein 1 Antibody, Tax-binding protein 181 Antibody, TP53I9 Antibody, PIG9 Antibody, HSMAD1 Antibody, Tax1-binding protein txbp181 Antibody, TXBP181 Antibody


Specifications

Target
Human MAD1L1 / MAD1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [9B10]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Immunofluorescence (1:500 - 1:1000) & (1 - 2 µg/ml)
  • Western blot
  • Immunoprecipitation
Immunogen
MAD1L1 / MAD1 antibody was raised against recombinant full length MAD1 protein (human).
Specificity
Human MAD1
Presentation
PBS, 0.1% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.
Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.

Western blot

Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.
Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.

Western blot

Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.
Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.

Western blot

Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.
Anti- Mad1L1 monoclonal antibody. Western blot of Mad1L1 expression in A-431.


Requested From: 
Date Requested: 6/25/2018

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