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Anti-Macrophage Antibody (clone TRPM3) LS-C96400

Ordering

Wt. Vol. Conc. Price
100 µg - - $475
Inquire for larger quantities

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206-374-1102
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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone TRPM3]
Rat
IHC - Frozen
Unconjugated

Details

Macrophage
Mouse
Rat (tested or 100% immunogen sequence identity)
Monoclonal [TRPM3]
Unconjugated
Affinity purified
Unmodified

Applications

IHC - Frozen (1:400 - 1:800)

Specificity and Use

Macrophage antibody was raised against peritoneal macrophages
TRPM-3 recognizes an epitope of a membrane protein which is associated with a receptor for glycoconjugates (sialoadhesin). Antigen distribution: Isolated cells: TRPM-3 is negative with monocytes and granulocytes. Tissue sections: TRPM-3 stains marginal zone macrophages and marginal metallophils of the spleen strongly. It rarely reacts with cordal macrophages in the red pulp and interdigitating cells in the periarterial lymphatic sheath of the spleen. In lymph nodes, only sinus macrophages express the antigen. Moreover, it is expressed on macrophages in the synovial membrane, mucosa and submucosa of the gastrointestinal tract, twisted spindle-shaped macrophages of the omentum and on macrophages in the dermis and subcutaneous tissue. It is absent from macrophages in the thymus, Peyer's patches and from Langerhans cells in the skin. Specificity: Rat: macrophages Other species: negative in human, mouse, hamster, guinea- pig, goat, rabbit.

Packaging

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
0.5ml distilled water
Store at 4°C.
For research use only.

About Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MF), are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884.

Requested From: United States
Date Requested: 12/3/2016

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