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Anti-Macrophage Antibody (clone Ki-M2R) LS-C96396

Ordering

Wt. Vol. Conc. Price
100 µg - - $515
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone Ki-M2R]
Rat
IHC - Paraffin
Unconjugated

Details

Macrophage
Mouse
Rat (tested or 100% immunogen sequence identity)
Monoclonal [Ki-M2R]
Unconjugated
Affinity purified
Unmodified

Applications

IHC - Paraffin (1:400)

Specificity and Use

Macrophage antibody was raised against peritoneal macrophages
Ki-M2R recognizes a surface antigen of 45kD molecular weight as a single band under reducing conditions. The epitope has not been further characterized Antigen distribution: Isolated cells: In the bone marrow a minor number of macrophages reveal a strong reactivity whereas granulocytes, erythropoetic cells and megacaryocytes are negative. Immature accessory cells such as dendritic or interdigitating reticulum cells are also negative. Monocytes show a positive reaction when exposed to TPA or foreign material. Tissue sections: Ki-M2R positive cells have been recognised as active phagocytes in serous cavities (peritoneal and pleural macrophages). Liver (Kupffer cells), spleen (macrophages of the red pulp), lymph nodes (macrophages of the pulp and sinus, tingible body macrophages), lung (approx. 50% of alveolar macrophages) and connective tissue (histiocytes) are positively stained. Plasma cells (excluding stimulated monocytes) as well as sinus lining cells are negative. Specificity: Rat: mature macrophages. Other species: not tested

Packaging

Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.09% sodium azide
0.5ml distilled water
Store at 4°C.
For research use only.

About Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MF), are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884.

Immunohistochemistry

Immunohistochemistry
IHC of Macrophages antibody LS-C96396. Frozen section rat colon.

Immunohistochemistry

Immunohistochemistry
IHC of Macrophages antibody LS-C96396. Frozen section of rat skin.

Immunohistochemistry

Immunohistochemistry
IHC of Macrophages antibody LS-C96396. Frozen section of rat spleen.
 

Requested From: United States
Date Requested: 12/4/2016

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