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Anti-LTB4R2 / BLT2 Antibody (Cytoplasmic Domain) IHC-plus™ LS-A2099

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human LTB4R2 / BLT2
Human, Monkey
IHC - Paraffin, Flow Cytometry
Unconjugated

Details

Human LTB4R2 / BLT2
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (26 µg/ml), Flow Cytometry

Specificity and Use

LTB4R2 / BLT2 antibody was raised against synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human LTB4R2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Mouse, Rat, Bat (88%); Elephant (81%).
LS-E28494 - Liquid - 50 µg - $145.00
Cytoplasmic Domain
Human LTB4R2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (2)

1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Bck M, Bu DX, Brnstrm R, Sheikine Y, Yan ZQ, Hansson GK. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:17501-6. (IHC-Fr; Human) [PubMed:16293697] [PMC:PMC1297663]
2
Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2. Seo JM, Park S, Kim JH. The Journal of biological chemistry. 2012 Apr;287:13840-9. [Full Text Article] [PubMed:22396544] [PMC:PMC3340142]

About LTB4R2 / BLT2

Q9NPC1 NM_019839 NP_062813.2

LTB4R2 Antibody, BLT2 Antibody, BLTR2 Antibody, Blt-2 Antibody, BLT2R Antibody, JULF2 Antibody, LTB4-R2 Antibody, Hblt2 Antibody, KPG_004 Antibody, Leukotriene B4 receptor 2 Antibody, Leukotriene B4 receptor BLT2 Antibody, LTB4 receptor JULF2 Antibody, LTB4-R 2 Antibody

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Immunohistochemistry

Immunohistochemistry
Anti-LTB4R2 / BLT2 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-LTB4R2 / BLT2 antibody IHC of human Colon, Carcinoma and Leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-LTB4R2 antibody LS-A2099 IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/25/2016

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