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Anti-LRRK2 Antibody (aa1838-2133) IHC-plus™ LS-B124

Note: This antibody replaces LS-C18626
See our new LRRK2 ELISA Kits
Human LRRK2 ELISA Kit - LS-F7866
Rat LRRK2 ELISA Kit - LS-F9745
(kits do not necessarily contain the antibody listed on this page)

Ordering

Wt. Vol. Conc. Price
50 µg - - $395

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

LRRK2 Antibody LS-B124 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-LRRK2 antibody IHC of human kidney.
Immunohistochemistry
Anti-LRRK2 antibody IHC of human pancreas.

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Rabbit Polyclonal to Human LRRK2
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Human LRRK2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Protein A purified

Applications

IHC - Paraffin (5 µg/ml), Western blot (1:1000), Immunoprecipitation (1:100)

Specificity and Use

LRRK2 antibody was raised against recombinant human LRRK2 (leucine-rich repeat kinase 2) (aa 1838-2133).
aa1838-2133
The strongest recognized epitope is PDQPRLTIPISQ (aa 1843-1854) as defined by epitope mapping.
Immunohistochemistry: LS-B124 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B124 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About LRRK2

Q5S007 NM_198578 NP_940980.3

LRRK2 Antibody, AURA17 Antibody, PARK8 Antibody, RIPK7 Antibody, ROCO2 Antibody, DARDARIN Antibody, Leucine-rich repeat kinase 2 Antibody

Mutations in the leucine-rich repeat kinase 2 (LRRK2) cause late onset Parkinson's disease (PD) also known as autosomal-dominant Parkinsonism with clinical features of PD and with pleomorphic pathology including deposits of aggregated protein. LRRK2 has been shown to interact with Parkin 2.

Immunohistochemistry

Immunohistochemistry
Anti-LRRK2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B124 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-LRRK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B124 concentration 5 ug/ml.

Requested From: United States
Date Requested: 4/19/2015

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