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Anti-LRRK2 Antibody (C-Terminus, clone 133AT720, Azide-free, HRP) LS-C249340


Wt. Vol. Conc. Price
- 100 µl - $545

LSBio (Direct) LSBio (Direct)

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Mouse Monoclonal [clone 133AT720] (IgG1) to Human LRRK2
Human, Mouse
Western blot, ELISA
HRP Conjugated Azide-free


Human LRRK2
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [133AT720]
Horseradish Peroxidase
Affinity purified


Western blot, ELISA

Specificity and Use

LRRK2 antibody was raised against his-tagged recombinant protein comprising of the C-terminal 261 residues of human LRRK2.
Human LRRK2.
The applications listed above are for the unconjugated form of this antibody. The conjugated antibody has not been tested.


PBS, pH 7.2, azide-free.
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C.
For research use only.

About LRRK2

Q5S007 NM_198578 NP_940980.3

LRRK2 Antibody, AURA17 Antibody, PARK8 Antibody, RIPK7 Antibody, ROCO2 Antibody, DARDARIN Antibody, Leucine-rich repeat kinase 2 Antibody

Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

Requested From: United States
Date Requested: 11/27/2015

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