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LRP1 / CD91
low density lipoprotein receptor-related protein 1
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
| Gene Name: | low density lipoprotein receptor-related protein 1 |
| Synonyms: | LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1, LRP-85, LRP-515, LRPICD |
| Target Sequences: | NM_002332 NP_002323.2 Q07954 |
Publications (2)
1
ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment. Chi-Lam Au-Yeung, Tsz-Lun Yeung, Abhinav Achreja, Hongyun Zhao, Kay-Pong Yip, Suet-Ying Kwan, Michaela Onstad, Jianting Sheng, Ying Zhu, Dodge L Baluya, Ngai-Na Co, Angela Rynne-Vidal, Rosemarie Schmandt, Matthew L Anderson, Karen H Lu, Stephen T C Wong, Deepak Nagrath, Samuel C Mok. Nature communications. 2020 July;11:3546. [Full Text Article]
[PubMed:32669559]
[PMC:PMC7363861]
Related Antibodies: LS-B2675.
2
Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis. Po-Hsuan Lai, Ting-Hsuan Wang, Nai-You Zhang, Kuo-Chen Wu, Chung-Chen Jane Yao, Chun-Jung Lin. Journal of neuroinflammation. 2021 Jan;18:35. [Full Text Article]
[PubMed:33516259]
[PMC:PMC7847579]
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LRP1 / CD91 Mouse anti-Human Monoclonal (5A6) Antibody
Rabbit, Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$515
LRP1 / CD91 Mouse anti-Human Monoclonal (Biotin) (5A6) Antibody
Rabbit, Mouse, Human
ELISA, Flo, ICC, IF, IHC, IHC-Fr, IHC-P, IP
Biotin Conjugated
100 µg/$414; 1 mg/$2,168
LRP1 / CD91 Mouse anti-Human Monoclonal (FITC) (5A6) Antibody
Rabbit, Mouse, Human
ELISA, Flo, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
100 µg/$414; 1 mg/$2,168
LRP1 / CD91 Mouse anti-Human Monoclonal (MA-8G1) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.25 mg/$555
LRP1 / CD91 Mouse anti-Human Monoclonal (Biotin) (8G1) Antibody
Human
DB, EM, Flo, IF, IHC, IHC-Fr, IHC-P, WB
Biotin Conjugated
100 µg/$414; 1 mg/$2,168
LRP1 / CD91 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$625
LRP1 / CD91 Mouse anti-Human Monoclonal (Azide-free) (A2Mralpha-2) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Azide-free
50 µl/$485
LRP1 / CD91 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$786
LRP1 / CD91 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, IHC, WB
PE Conjugated
100 µl/$1,017
LRP1 / CD91 Mouse anti-Human Monoclonal (APC) (6A34) Antibody
Human
ELISA, IF, IHC, WB
APC Conjugated
100 µl/$1,017
E. coli
His, N-Terminal
33.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
E. coli
His
13.0 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
Sandwich
96-Well Microplate
Mouse
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
293T Cells
Myc-DDK (Flag)
504.61 kDa
20 µg/$215
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LRP1 / CD91 Rabbit anti-Human Polyclonal (aa20-270) Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
LRP1 / CD91 Rabbit anti-Mouse Polyclonal (aa337-426) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
LRP1 / CD91 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100 µg/$475
LRP1 / CD91 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$890
LRP1 / CD91 Mouse anti-Human Monoclonal (MA-8B8) Antibody
Rabbit, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1 mg/$682; 10 mg/$4,719
LRP1 / CD91 Mouse anti-Human Monoclonal (FITC) (8B8) Antibody
Rabbit, Human
Flo, IF, IHC, IHC-P, WB
FITC Conjugated
100 µg/$414; 1 mg/$2,168
HEK 293 Cells
Myc-DDK (Flag)
504.61 kDa
100 µg/$710
LRP1 / CD91 Mouse anti-Human Monoclonal (5A6) Antibody
Rabbit, Mouse, Human
Flo, IHC, WB
Unconjugated
500 µg/$711; 1 mg/$1,135
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