Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone A2Mr alpha-2] (IgG1) to Human LRP1 / CD91
Human LRP1 / CD91
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [A2Mr alpha-2]
Specificity and Use
LRP1 / CD91 antibody was raised against purified alpha2 macroglobulin receptor.
Recognizes human CD91 a type I membrane protein which is also known as the alpha 2 macroglobulin receptor (alpha 2MR). MON 4074R recognizes an epitope in the extracellular region of the 500kD alpha chain.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.