Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
LPPR4 / PRG1 antibody was raised against recombinant human PRG-1 E. coli-derived rhPRG-1.
Recognizes human PRG-1.
Suitable for use in Direct ELISA and Western Blot. Direct ELISA: 0.5-1 ug/mL detection limit for rhPRG-1 ~5 ng/well. Western Blot: 1-2 ug/mL detection limit for rhPRG-1 ~10 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul 40-50% glycerol, PBS.
LPPR4 / PRG1 belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.