Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Lysyl Oxidase / LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I).
Anti-Lysyl Oxidase / LOX antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8037 dilution 1:100. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry: LOX propeptide Antibody LOX propeptide staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue).. This image was taken for the unconjugated form of this product. Other forms have not been tested.
LOX propeptide Antibody - Western blot of LOX propeptide on MDA-MB-231. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FACS staining of NTERA-2 cells using NP1-30327 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.