Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Zebrafish (at least 90% immunogen sequence identity)
Specificity and Use
LMO2 antibody was raised against synthetic peptide made to an N-terminal portion of the human protein (within residues 1-100). [Swiss-Prot# P25791]. Percent identity by BLAST analysis: Zebrafish (93%).
LMO2 Antibody, LIM domain only protein 2 Antibody, LMO-2 Antibody, RHOM2 Antibody, RBTNL1 Antibody, Rhombotin 2 Antibody, Rhombotin-like 1 Antibody, Cysteine-rich protein TTG-2 Antibody, RBTN2 Antibody, Rhombotin-2 Antibody, T-cell translocation gene 2 Antibody, T-cell translocation protein 2 Antibody, TTG2 Antibody
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur.