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Anti-LMNA / Lamin A+C Antibody (aa59-572) LS-C186225

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Rabbit Polyclonal to Human LMNA / Lamin A+C
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human LMNA / Lamin A+C
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (1:100 - 1:1000), Western blot (1:500 - 1:3000)

Specificity and Use

LMNA / Lamin A+C antibody was raised against recombinant fragment contain a sequence corresponding to a region within amino acids 59 and 572 of Lamin A/C.
aa59-572
Human LMNA / Lamin A/C
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).

Packaging

0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About LMNA / Lamin A+C

P02545 NM_005572 NP_005563.1

LMNA Antibody, 70 kDa lamin Antibody, CDCD1 Antibody, CMD1A Antibody, EMD2 Antibody, FPLD Antibody, IDC Antibody, FPL Antibody, FPLD2 Antibody, Lamin A/C Antibody, Lamin Antibody, LFP Antibody, LMNC Antibody, LMN1 Antibody, LMNL1 Antibody, HGPS Antibody, Prelamin-A/C Antibody, PRO1 Antibody, Lamin A Antibody, Lamin A/C-like 1 Antibody, LGMD1B Antibody, CDDC Antibody, CMT2B1 Antibody, LDP1 Antibody

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded H441 Xenograft using Lamin A/C antibody at 1:100 dilution.

Western blot

Western blot
Lamin A/C antibody detects LMNA protein by Western blot analysis. A. 30 ug NIH-3T3 whole cell lysate/extract. 7.5 % SDS-PAGE. Lamin A/C antibody dilution:1:1000

Western blot

Western blot
Sample (20 ug ). A: HeLa Nucleus. 10% SDS PAGE. LMNA / Lamin A/C antibody diluted at 1:3000.
 

Requested From: United States
Date Requested: 5/30/2016

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