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Catalog Number Size Price
LS-C25083-100 100 µl $689 
Antibody

Monoclonal Mouse anti‑Human LMNA / Lamin A+C Antibody (N‑Terminus, IF, WB) LS‑C25083

Monoclonal Mouse anti‑Human LMNA / Lamin A+C Antibody (N‑Terminus, IF, WB) LS‑C25083

Antibody:
LMNA / Lamin A+C Mouse anti-Human Monoclonal (N-Terminus) Antibody
Application:
ICC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$689
LS-C25083-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
LMNA / Lamin A+C Mouse anti-Human Monoclonal (N-Terminus) Antibody
Application:
ICC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Lamin A+C antibody LS-C25083 is an unconjugated mouse monoclonal antibody to Lamin A+C (LMNA) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for ICC, IF and WB.
Target
Human LMNA / Lamin A+C
Synonyms
LMNA | 70 kDa lamin | CDCD1 | CMD1A | EMD2 | FPLD | IDC | FPL | FPLD2 | Lamin A/C | Lamin | LFP | LMNC | LMN1 | LMNL1 | HGPS | Prelamin-A/C | PRO1 | Lamin A | Lamin A/C-like 1 | LGMD1B | CDDC | CMT2B1 | LDP1
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to N-Terminus residues adjacent to Asp230 in human lamin A.
Epitope
N-Terminus
Specificity
Detects endogenous levels of the small fragment of lamin A when cleaved by caspase-6 at Asp230. It is a marker of caspase-6 activity. Detects the small fragment of lamin A/C only when cleaved at Asp230. Does not cross-react with full length lamin A (nor with lamin C). Species cross-reactivity: Mouse and rat.
Applications
  • ICC
  • Immunofluorescence (1:1000)
  • Western blot (1:1000)
Usage
Western Blot: 1:1000. Immunocytochemistry (ABC) 1:1000. Immunocytochemistry (IF) 1:1000.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About LMNA / Lamin A+C
P02545 NM_005572 NP_005563.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/23/2024