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Anti-LIN28B Antibody (aa218-250) LS-C98241

Catalog Size Price
LS-C98241-400 400 µl Unavailable

Related Products

25 LIN28B Antibodies

Most Popular LIN28B Antibodies

Anti-LIN28B Antibody (aa1-30) IHC-plus™ LS-B3423
Rabbit Polyclonal to Human LIN28B
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-LIN28B Antibody (aa6-36, AP) LS-C237137
Rabbit Polyclonal (IgG) to Human LIN28B
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IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
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Anti-LIN28B Antibody (aa6-36, APC) LS-C237138
Rabbit Polyclonal (IgG) to Human LIN28B
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IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
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Anti-LIN28B Antibody (aa6-36, Biotin) LS-C237139
Rabbit Polyclonal (IgG) to Human LIN28B
Human
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
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Anti-LIN28B Antibody (aa6-36, PE) LS-C237140
Rabbit Polyclonal (IgG) to Human LIN28B
Human
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
PE Conjugated

100% Guaranteed
Rabbit Polyclonal to Human LIN28B
Human
Western blot, Flow Cytometry
Unconjugated

Details

Human LIN28B
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E3658 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C98241. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa218-250
This LIN28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-250 amino acids from the C-terminal region of human LIN28B.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About LIN28B

Q6ZN17 NP_001004317.1

LIN28B Antibody, CSDD2 Antibody, Lin-28B Antibody, Lin-28 homolog B (C. elegans) Antibody, Protein lin-28 homolog B Antibody, Lin-28.2 Antibody

Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7.

Western blot

Western blot
Western blot of LIN28B Antibody in HL60 cell line lysates (35 ug/lane). LIN28B (arrow) was detected using the purified antibody.

Flow Cytometry

Flow Cytometry
Flow cytometric of HL-60 cells using LIN28B Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 12/16/2017

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