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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LIMPII / SCARB2 Antibody (C‑Terminus) IHC‑plus™ LS‑B305
Note: This antibody replaces LS-C2706
SCARB2 antibody LS-B305 is an unconjugated rabbit polyclonal antibody to SCARB2 (LIMPII) from human, mouse, rat and other species. Validated for ICC, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Catalog
Size
Price
LS-B305-100
100 µl
$425

Popular LIMPII / SCARB2 Products

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Species: Human
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Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA619859LA01HU at dilution of 1:100
Species: Human, Mouse
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Anti-LIMPII / SCARB2 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8260 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Gibbon, Bovine, Pig
Applications: IHC, IHC - Paraffin, Western blot

Product Description

SCARB2 antibody LS-B305 is an unconjugated rabbit polyclonal antibody to SCARB2 (LIMPII) from human, mouse, rat and other species. Validated for ICC, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
About LIMPII / SCARB2
LIMPII / SCARB2 is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Q14108 NM_005506 NP_005497.1

SCARB2 Antibody, AMRF Antibody, CD36 antigen-like 2 Antibody, LGP85 Antibody, Lysosome membrane protein 2 Antibody, LIMPII Antibody, HLGP85 Antibody, LIMP-2 Antibody, SR-BII Antibody, CD36 antigen Antibody, CD36L2 Antibody, EPM4 Antibody, LIMP II Antibody, Lysosome membrane protein II Antibody


Specifications

Target
Mouse LIMPII / SCARB2
Host
Rabbit
Reactivity
Mouse, Human, Rat, Dog (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:500)
  • ICC (1:250)
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
LIMPII / SCARB2 antibody was raised against a C-terminal synthetic peptide made to the mouse LIMPII/lgp85 protein sequence
Epitope
C-Terminus
Specificity
Mouse and human LIMPII/lgp85.
Usage
Immunohistochemistry: LS-B305 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B305 was determined to be 1:500.
Presentation
Whole antiserum with 0.05% Sodium Azide
Storage
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (2)

1
Distinctive histopathological features that support a diagnosis of cholesterol ester storage disease in liver biopsy specimens. H[Character 16f]lkov[Character e1] H, Elleder M. Histopathology. 2012 Jun;60:1107-13. [Full Text Article] [PubMed:22621222]
2
Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice. Kook S, Wang P, Young LR, Schwake M, Saftig P, Weng X, Meng Y, Neculai D, Marks MS, Gonzales L, Beers MF, Guttentag S. The Journal of biological chemistry. 2016 291:8414-27. (ICC, WB; Mouse, Human) [Full Text Article] [PubMed:26907692]

Customer Reviews (0)


Images

Immunohistochemistry

Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.
Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.

Immunohistochemistry

Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.
Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.

Immunohistochemistry

Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.
Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.

Immunohistochemistry

Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.
Anti-SCARB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B305 concentration 1:500.

Requested From: United States
Date Requested: 8/19/2018

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