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Catalog Number	Size	Price
LS-C204201-0.1	0.1 mg (1 mg/ml)	$545

Polyclonal Rabbit anti‑Human LIME1 / LIME Antibody (Concentrated, aa141‑295, WB) LS‑C204201

Name: Anti-LIME1 / LIME Antibody | Rabbit anti-Human Polyclonal WB | LSBio
Brand: Lifespan BioSciences
SKU: LS-C204201-0.1
Price: 545.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Antibody:

LIME1 / LIME Rabbit anti-Human Polyclonal (aa141-295) (Concentrated) Antibody

Application:

Reactivity:

Human

Format:

Unconjugated, Concentrated

$545

LS-C204201-0.1

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

LIME1 / LIME Rabbit anti-Human Polyclonal (aa141-295) (Concentrated) Antibody

Application:

Reactivity:

Human

Format:

Unconjugated, Concentrated

Specifications

Description

LIME antibody LS-C204201 is an unconjugated rabbit polyclonal antibody to human LIME (LIME1) (aa141-295). Validated for WB.

Target

Human LIME1 / LIME

Synonyms

LIME1 | DJ583P15.4 | Lck-interacting molecule | LIME | RP4-583P15.5 | LP8067

See All LIME1 / LIME Antibodies

Host

Rabbit

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

Polyclonal

Conjugations

Unconjugated

Purification

Purified

Modifications

Concentrated

Immunogen

Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME

Epitope

aa141-295

Specificity

LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation.

Applications