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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LILRB3 Antibody (clone 4F9, RPE) LS‑C58078
LILRB3 antibody LS-C58078 is an RPE-conjugated mouse monoclonal antibody to human LILRB3. Validated for Flow and IHC.
Antibody
Catalog
Size
Price
LS-C58078-100
100 tst
$495

Popular LILRB3 Products

Western blot of recombinant LILRB3 / PIRB.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, Western blot
Immunofluorescence staining of NIH/3T3 cells diluted at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Species: Human
Applications: Immunofluorescence, Western blot, ELISA
Antibody
Species: Mouse
Applications: ICC, Immunofluorescence, Flow Cytometry
Antibody
Species: Human
Applications: IHC, IHC - Frozen, Flow Cytometry
Antibody
Species: Human
Applications: IHC, IHC - Frozen, Flow Cytometry

Product Description

LILRB3 antibody LS-C58078 is an RPE-conjugated mouse monoclonal antibody to human LILRB3. Validated for Flow and IHC.
About LILRB3
LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). O75022 NM_006864 NP_006855.3

LILRB3 Antibody, CD85A Antibody, CD85a antigen Antibody, ILT5 Antibody, LIR-3 Antibody, LIR3 Antibody, Monocyte inhibitory receptor Antibody, HL9 Antibody, ILT-5 Antibody


Specifications

Target
Human LILRB3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [4F9]
Conjugations
R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Flow Cytometry (1:1 - 1:5)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
LILRB3 antibody was raised against monocyte derived dendritic cells.
Specificity
Specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.
Presentation
Lyophilized PBS, pH 7.4, 0.09% Sodium Azide, 1% BSA
Reconstitution
100 tst Distilled Water.
Storage
Store at 4°C. Avoid freezing.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/24/2018

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