Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human LIG4 / DNA Ligase IV
IHC, Immunofluorescence, Western blot, ELISA
Rabbit Polyclonal to Human LIG4 / DNA Ligase IV
IHC - Paraffin, Western blot, ELISA
Human LIG4 / DNA Ligase IV
Human (tested or 100% immunogen sequence identity)
Protein A purified
IHC - Paraffin
Specificity and Use
LIG4 / DNA Ligase IV antibody was raised against synthetic peptide derived from a region between residues 275 - 324 of human DNA Ligase IV.
Recognizes human RBM25.
Suitable for use in ELISA, Western Blot and Immunohistochemistry (paraffin-embedded sections).
PBS, 2% sucrose
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C
LIG4 Antibody, DNA ligase IV Antibody, DNA joinase Antibody, DNA ligase 4 Antibody, DNA repair enzyme Antibody, Ligase IV, DNA, ATP-dependent Antibody, Sealase Antibody, Polynucleotide ligase Antibody
LIG4 / DNA Ligase IV is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ.