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LIG1 / DNA Ligase 1

ligase I, DNA, ATP-dependent

LIG1 / DNA Ligase 1 is a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Gene Name: ligase I, DNA, ATP-dependent
Synonyms: LIG1, DNA ligase I, DNA ligase 1, Ligase I, DNA, ATP-dependent
Target Sequences: NM_000234 NP_000225.1 P18858

☰ Filters
Antibodies (62)
Proteins (7)
ELISA Kits (4)
Custom (2)
Over-Expression Lysate (2)
Primary (62)
Recombinant (5)
Sandwich (2)
LIG1 / DNA Ligase 1 (73)
Human (63)
Mouse (11)
Rat (16)
Bat (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Hamster (1)
Monkey (7)
Rabbit (6)
IHC (13)
IHC-P (6)
WB (59)
ELISA (15)
IF (3)
IP (4)
Peptide-ELISA (4)
rabbit (57)
mouse (4)
goat (1)
Product Group
IHCPlus (3)
IgG (27)
IgG1 (1)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (59)
10G12 (1)
10H5 (1)
96-Well Strip Plate (4)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (7)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Unconjugated (27)
aa484-663 (8)
aa568-875 (8)
aa739-995 (8)
aa1-30 (7)
aa578-627 (4)
aa611-660 (4)
80-160 aa, N-terminal (1)
Glu139 (1)
N-Terminus (1)
aa1-919 (1)
aa111-160 (1)
aa200-250 (1)
aa51-68 (1)
aa877-890 (1)
aa90-139 (1)
No (73)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
LIG1 / DNA Ligase 1 Antibody - Anti-LIG1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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LIG1 / DNA Ligase 1 Mouse anti-Human Monoclonal (10G12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
LIG1 / DNA Ligase 1 Antibody - Anti-LIG1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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LIG1 / DNA Ligase 1 Mouse anti-Human Monoclonal (10H5) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
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LIG1 / DNA Ligase 1 Mouse anti-Human Monoclonal (aa1-919) Antibody
Human
IP, WB
Unconjugated
100 µg/$563
LIG1 / DNA Ligase 1 Antibody - Immunofluorescence analysis of MCF7 cells.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
LIG1 / DNA Ligase 1 Antibody - LIG1 antibody (0.1 ug/ml) staining of HeLa nuclear lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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LIG1 / DNA Ligase 1 Goat anti-Human Polyclonal (aa877-890) Antibody
Rat, Hamster, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
LIG1 / DNA Ligase 1 Antibody - Anti-DNA Ligase 1 / LIG1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa111-160) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
LIG1 / DNA Ligase 1 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
LIG1 / DNA Ligase 1 Protein - Recombinant ATP Dependent DNA ligase I By SDS-PAGE
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E. coli
His, N-Terminal
24.4 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
LIG1 / DNA Ligase 1 Antibody - Western blot of DNA Ligase I antibody
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (80-160 aa, N-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LIG1 / DNA Ligase 1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using DNL1 antibody.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
LIG1 / DNA Ligase 1 Antibody - Western blot analysis of the lysates from HepG2 cells using DNL1 antibody.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa90-139) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LIG1 / DNA Ligase 1 Antibody - IHC of DNA Ligase I (E139) pAb in paraffin-embedded human brain tissue.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (Glu139) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
LIG1 / DNA Ligase 1 Antibody - Immunohistochemical analysis of DNA Ligase 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
LIG1 / DNA Ligase 1 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using LIG1 Polyclonal Antibody at dilution of 1:70.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
LIG1 / DNA Ligase 1 Antibody - Detection of Human DNA Ligase 1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-DNA Ligase 1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa200-250) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LIG1 / DNA Ligase 1 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using LIG1 Antibody at dilution of 1:100
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LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
LIG1 / DNA Ligase 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 73 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).