Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone M3/38] (IgG2a,k) to Mouse LGALS3 / Galectin 3
Mouse LGALS3 / Galectin 3
Mouse (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [M3/38]
Specificity and Use
LGALS3 / Galectin 3 antibody was raised against mouse LGALS3
This M3/38 (M3/38) antibody has been tested by intracellular staining and flow cytometric analysis. This can be used at less than or equal to 0.25 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Staining can be done using Foxp3 buffers or IC Fixation Buffers.
LGALS3 / Galectin 3 is a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands.
Intracellular staining of the monocyte population in human PBMCs or C57 mouse bone marrow cells (left) with APC anti-mouse CD11b (M1/70) (LS-C107298) and 0.125 ug of Biotin anti-mouse Galectin-3 (M3/38)followed by SAv-PE. Total viable cells were used for analysis.
Intracellular staining of the monocyte population in human PBMCs (right) or C57 mouse bone marrow cells followed by SAv-PE. Total viable cells were used for analysis.
Requested From: United States
Date Requested: 10/27/2016