Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone A70-C/C8] (IgM) to Human Lewis y / CD174
IHC - Paraffin, IHC - Frozen
Human Lewis y / CD174
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [A70-C/C8]
IHC - Paraffin
IHC - Frozen
Specificity and Use
Lewis y / CD174 antibody was raised against live cells of the human colorectal carcinoma cell line Ls174T.
Recognizes the epitope Fuc-a-1-2Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1 of the human blood group Lewis Y. Does not cross react with the blood group H type 2 antigens or with Lea, sialyl-Lea, Lex, sialyl-Lex, Leb or Lec.
Suitable for use in Immunohistochemistry: Frozen, paraffin.
PBS, 0.05% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months