Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 7LE] (IgG1) to Human Lewis A Blood Group Antigen
IHC - Paraffin, Western blot, ELISA
Human Lewis A Blood Group Antigen
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [7LE]
Protein A purified
IHC - Paraffin
Specificity and Use
Mucin isolated by size-exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification).
Recognizes Lewis a blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed in colonic epithelial cells. Lewis a may be useful for detection of gastrointestinal, pancreatic and colorectal tumors
Immunohistochemistry (paraffin sections): Recommended dilution - 5 ug/ml. Positive control - colorectal adenocarcinoma. Application note - heat mediated antigen retrieval (sodium citrate). mAb incubation 1 hour / RT. detection DAB.
PBS, 15 mM sodium azide, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.