Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3G1-1C9] (IgG2b,k) to Human Leptin
Western blot, ELISA
Rabbit Polyclonal (IgG) to Mouse Leptin
IHC - Paraffin, Western blot, ELISA
Mouse (tested or 100% immunogen sequence identity)
IHC - Paraffin
Western blot (0.1 - 0.2 µg/ml)
ELISA (0.5 µg/ml)
Specificity and Use
Leptin antibody was raised against recombinant mouse leptin.
Recognizes mouse leptin. Leptin (anti-obesity protein) is the product of the ob (obese) gene in mice and is involved in appetite control. The gene is expressed in adipose tissue and it is thought to be important in the regulation of fat stores. Mice of ob/ob genotype develop a form of diabetes similar to type II (non-insulin dependant) diabetes.
LEP Antibody, Leptin Antibody, LEPD Antibody, Obese protein Antibody, Obese, mouse, homolog of Antibody, Obesity factor Antibody, OBS Antibody, OB Antibody
Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing.