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Anti-LDLR / LDL Receptor Antibody LS-C8504

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Mouse Monoclonal (IgG2b,k) to Bovine LDLR / LDL Receptor
Bovine, Human
Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated

Details

Bovine LDLR / LDL Receptor
Mouse
Bovine, Human (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal
Immunoaffinity purified

Applications

Immunofluorescence, Western blot (0.1 - 1 µg/ml), Flow Cytometry, ELISA

Specificity and Use

LDLR / LDL Receptor antibody was raised against purified bovine adrenal cortex LDL Receptor.
Recognizes an epitope in the region of repeat #1 of the ligand binding region. Species cross-reactivity: Human and bovine. Does not recognize rat, mouse, hamster, canine or rabbit.
Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunofluorescence Microscopy. Western Blot: 0.1-1 ug/ml using enhanced chemiluminescence detection. Due to low affinity of this antibody, extended incubation-overnight or longer at 4?C is recommended.

Packaging

Lyophilized powder from PBS, 0.5% BSA
50 µl 1 ml sterile ddH20
Store at -20°C lyophilized. Reconstitute with sterile 40-50% glycerol and ddH2O. Aliquot and store at -20°C.
For research use only.

About LDLR / LDL Receptor

P01130 NM_000527 NP_000518.1

LDLR Antibody, FHC Antibody, LDL receptor Antibody, LDLCQ2 Antibody

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis.

Requested From: United States
Date Requested: 9/28/2016

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