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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LDLR / LDL Receptor Antibody (clone 5E7) LS‑C197609
LDL Receptor antibody LS-C197609 is an unconjugated mouse monoclonal antibody to human LDL Receptor (LDLR). Validated for ELISA and WB.
Catalog
Size
Price
LS-C197609-100
100 µg
Unavailable

Popular LDLR / LDL Receptor Products

Antibody
Species: Bovine, Human
Applications: Immunofluorescence, Western blot, Flow Cytometry, ELISA
Anti-LDL Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1598 concentration 10 ug/ml.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Antibody
Species: Human
Applications: Flow Cytometry
Western blot of LDLR / LDL Receptor antibody LS-C146979. Lane 1, Jurkat cell lysates. Lane 2, NIH3T3 cell lysates.
Species: Human, Mouse, Rat, Bovine, Hamster
Applications: Western blot
Immunohistochemistry: LDL Receptor Antibody (C7) - Analysis of LDL Receptor on human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Bovine, Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation

Product Description

LDL Receptor antibody LS-C197609 is an unconjugated mouse monoclonal antibody to human LDL Receptor (LDLR). Validated for ELISA and WB.
About LDLR / LDL Receptor
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. P01130 NM_000527 NP_000518.1

LDLR Antibody, FHC Antibody, LDL receptor Antibody, LDLCQ2 Antibody


Specifications

Target
Human LDLR / LDL Receptor
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [5E7]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
LDLR (NP_000518, aa105-205 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human LDLR / LDL Receptor
Usage
Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.

Western blot

Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.

Western blot

Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.

Western blot

Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged LDLR is approximately 0.3 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/18/2018

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