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Anti-LCP2 / SLP-76 Antibody (aa216-434) LS-C44763


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular LCP2 / SLP-76 Antibodies

Anti-LCP2 / SLP-76 Antibody (aa216-434, clone SLP-76/03) IHC-plus™ LS-B1879
Mouse Monoclonal [clone SLP-76/03] (IgG2b) to Human LCP2 / SLP-76
Human, Mouse, Pig
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2b) to Human LCP2 / SLP-76
Human, Mouse, Pig
Western blot, Immunoprecipitation


Human LCP2 / SLP-76
Human, Mouse, Pig (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Protein G purified


  • Western blot (1:500)
  • Immunoprecipitation

Specificity and Use

LCP2 / SLP-76 antibody was raised against a fusion protein corresponding to amino acids 216-434 of human SLP-76.
Recognizes the SH2 domain-containing leucocyte protein (SLP-76), a 76kD tyrosine phosphoprotein, expressed primarily by T lymphocytes and cells of the myeloid lineage. SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC)-gamma, Vav, Nck and fyn binding protein.
Western Blot: LS-C44763 detects a band of approximately 76kD in T lymphocyte cell lysates.


PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About LCP2 / SLP-76

Q13094 NM_005565 NP_005556.1

LCP2 Antibody, 76 kDa tyrosine phosphoprotein Antibody, Lymphocyte cytosolic protein 2 Antibody, SLP-76 Antibody, SLP-76 tyrosine phosphoprotein Antibody, SLP76 Antibody

SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains.

Requested From: United States
Date Requested: 10/27/2016

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