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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LCMT2 / YW4 Antibody (N‑Terminus) LS‑C144383 Best Seller
YW4 antibody LS-C144383 is an unconjugated rabbit polyclonal antibody to YW4 (LCMT2) from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C144383-100
100 µg (1 mg/ml)
Unavailable

Popular LCMT2 / YW4 Products

Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

YW4 antibody LS-C144383 is an unconjugated rabbit polyclonal antibody to YW4 (LCMT2) from human and mouse. Validated for IHC and WB.
About LCMT2 / YW4
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues. O60294 NM_014793 NP_055608.2

LCMT2 Antibody, TRNA-yW synthesizing protein 4 Antibody, TYW4 Antibody, PPM2 Antibody, KIAA0547 Antibody


Specifications

Target
Human LCMT2 / YW4
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E31129 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C144383. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
TYW4 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW4 are known to exist; this antibody will detect only the long isoform.
Presentation
PBS, 0.02% sodium azide
Storage
Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 ug/ml.

Immunohistochemistry

Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.
Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 µg/mL.

Immunofluorescence

Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.
Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 ug/ml.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Western blot

Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.


Requested From: 
Date Requested: 6/20/2018

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